Herpes zoster: The vaccine is now available in private clinics in Brazil

A vaccine has been launched in Brazil this month blade it is now available in private clinics across the country. It is a late onset of those with the disease and often affects people over the age of 50 or immunocompromised patients. It should be given in two doses, with a two-month interval between applications.

THE Shingrix received regulatory approval National Agency for Health Care (Anvisa) August 2021 for the prevention of herpes zoster for adults over the age of 50 and adults 18 years of age and older who are at higher risk for the disease, such as immunocompromised patients receiving cancer treatment, people living with HIV, bone marrow or organ transplants, lupus, multiple sclerosis, among others.

Each application costs around R $ 843 on the private network. With the two-dose regimen, which spans two months, the total cost is around R $ 1,686. In addition to technology, the change in the exchange rate is also reflected in the final price of the immunizer. According to the pharmaceutical company GSK, the value may vary depending on the ICMS and the pricing practice of private clinics in each region of the country. The distribution of the vaccine has begun, with a considerable supply throughout Brazil until July.

“It is undeniable that the impact of new technologies on vaccine production has led to significant advances in the health of the population. , President of the Association of Brazilian Vaccine Clinics (ABCVAC), reinforcing that the use should be made in accordance with the medical prescription and recommendation included in the package.

“Cobra”

In addition to discomfort, pain, and skin lesions, herpes zoster, also called shingles, can never cause serious damage. If left untreated, the disease can lead to serious complications in the eyes, ears, and nerve endings in the face, leading to paralysis, hearing and vision loss. In Brazil, the issue is even more important, considering 35.4% increase in cases of reported illnessObserved in the Covid-19 pandemic.

“This person has had chickenpox or chickenpox, no matter when, but generally in childhood, and after going through the clinical picture, it is as if the varicella zoster virus has fallen asleep at one end of the nerve. At some point, in general, in the elderly, shingles appears. And when that happens, it usually has a nervous breakdown, “said Juarez Cunha, president of the Brazilian Immunization Association (Sbim).

Shingrix is ​​more than 90% effective in people over the age of 50 when they start attacking the virus. In the 50-69 age group, the effectiveness reaches 97%. It is the first herpes zoster vaccine to be used in people who have a weakened immune system and are more likely to develop the disease. in the case of zostavax, an ineffective vaccine from the MSD pharmaceutical company, which was not effective, was not allowed. “It was a weakened vaccine with an interesting effect, but it decreased as the person got older. He graduated from the age of 50. ambitionthe duration of the protection was not that long either, ”Juarez explained.

Shingrix, like the United States, is an inactivated vaccine used in other countries. “The advantage is that it can be applied to patients who are immunocompromised and licensed from the age of 18. And of course we recommend it to people between the ages of 18 and 50 who have a tendency to get the disease. In general, those who are immunocompromised. It is also recommended for people over the age of 18 as a regular vaccine. ”

In addition to Brazil, Shingrix is ​​already licensed for use in the European Union and in several countries, including the United States, Canada, Japan, China, New Zealand, Singapore, and Australia. “It’s already available in several countries and is very effective for people over the age of 50. In addition, it is a vaccine that is safe for people over the age of 18 who are immunocompromised, as it is not caused by a living virus, ”said Gunnar Riediger, head of GSK’s BioTech Business Unit.

At the moment, none of the vaccines are available Unique Health System (SUS).

What is herpes zoster?

Herpes zoster or shingles is a disease caused by the varicella-zoster virus, which also causes chickenpox. The virus remains dormant throughout a person’s life.

Reactivation occurs in people with adulthood or immunodeficiency, such as those with chronic diseases (hypertension, diabetes), cancer, AIDS, transplants, among others.

Exceptionally, there are patients who develop herpes zoster after contact with varicose vein patients and also with another shingles patient, which indicates the possibility of re-infection in someone who is already immunized. It is also possible for a child to come into contact with a sick shingles.

The disease can lead to complications and other serious clinical forms, including death.

What are the symptoms?

The clinical picture is almost always common. In most cases, the symptoms before the skin injury are:

  • me neuralgic (nerve).
  • paresthesias (supply, stinging, numbness and pressure)
  • local burns and itching
  • sugar
  • headache
  • discomfort

How is the diagnosis made?

Diagnosis is easy because the lesions affect the nerve endings. The supply starts with an itchy sensation and then goes into injury. Various skin lesions (small blisters on the skin) open and heal.

Other complications include post-herpetic neuralgia, a condition of many years of pain that lasts for many years. If it affects the nerve of the face, it can also cause vision damage.

How is the treatment done?

The sooner the diagnosis is made, the better the response to treatment. In general, with anti-virus use. An antipyretic analgesic, free of salicylates and a systemic antihistamine can be used to relieve pruritus (pus).

What are the preventive measures?

  • Vaccine (Children get vaccinated at 1 and 3 months of age and then at age 4. Sensitive teens and adults who have not had chickenpox should be vaccinated. It protects against chickenpox – no chickenpox, no shingles)
  • Wash your hands after touching the wounds
  • Isolation: Children with uncomplicated varicella should return to school only after all lesions have become indented. Children who are immunocompromised or have a long clinical course should return to activities only after the end of the vesicular rash.

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